The primary mechanisms by which blood flow occlusion training stimulates growth include: metabolic accumulation which stimulates a subsequent increase in anabolic growth factors, fast-twitch fiber recruitment (FT), and increased protein synthesis through the mammalian target of rapamycin (mTOR) pathway. Increases in heat
shock proteins (HSP), Nitric oxide synthase-1 (NOS-1), and decreased expression of Myostatin have also been observed.
Blood flow restriction training research thus far is promising with respect to safety outcomes. Individuals respond similarly to blood flow restriction training and to regular exercise.
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